Scientific Image Gallery
Welcome to our Scientific Image Gallery. Here you can find real-life examples of cell images, mostly (but not only) from peripheral blood films, that illustrate typical morphologic characteristics pointing to specific conditions or disorders. This constitutes their diagnostic value.
Click on an image to enlarge it and display a short description.
<p>In the impedance channel of a haematology analyser a falsely elevated platelet concentration of 850,000/μL was measured. This was caused by precipitated cryoglobulin in cryoglobulinaemia. The flocculated cryoglobulin is visible in the phase contrast microscope in between the red blood cell 'rouleaux'.</p>
<p>A large number of flocculated cryoglobulins become visible when the condenser is lowered and no microscope oil is applied.</p>
<p>Cell of a follicular lymphoma. The deeply indented nucleus is characteristic.</p>
<p>Fragmented red blood cells and thrombocytopenia in the case of a thrombotic thrombocytopenic purpura (TTP). In the partially thrombosed capillaries the red blood cells are exposed to a high degree of shearing force, which causes them to burst.</p>
<p>Blood film of a normal blood sample, which had frozen in the postbox. One can only recognise red blood cell 'shadows' or 'ghosts'.</p>
<p>Gametocyte in a patient infected with Plasmodium falciparum. </p>
<p>Bone marrow histology (periodic acid Schiff stain, PAS) displaying macrophages on the left, with a cytoplasm resembling crinkled parchment. They are so-called 'Gaucher' cells. Gaucher's disease is characterised by a congenital defect of the enzyme glucocerebrosidase leading to an increase of certain glycolipids (cerebrosides) inside the macrophages. On the right side of the picture the bone marrow appears normal.</p>
<p>Giant platelets have their name derived from their size exceeding the size of a normal red blood cell. </p>
<p>Giant platelet with prominent granulation from a patient with essential thrombocythaemia (ET). (Defective haematopoiesis causes detectable poikilocytosis.)</p>